6. "Now or Never"
As season five was starting to look up, things took a dramatic turn. In the season finale “Now or Never,” the outcome for Izzie Stevens and George O’Malley looks terrible. While O’Malley is fading fast after getting hit by a bus, and Stevens’ cancer looks like it’s finally taking her. Both meet, looking healthy, on an elevator going down. This finale left viewers wondering who would make it out alive.
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